---
title: Laser-Assisted Periodontal Therapy with a 9.3-μm CO2 Laser System
description: Human Clinical and Histologic Evaluations of Laser-Assisted Periodontal Therapy with a 9.3-μm CO² Laser System
---

[Clinical Studies | Convergent Dental ](https://www.convergentdental.com/clinical-studies)

# [Laser-Assisted Periodontal Therapy with a 9.3-μm CO2 Laser System](https://www.convergentdental.com/clinical-studies/clinical/human-clinical-and-histologic-evaluations-of-laser-assisted-periodontal-therapy-with-a-9-3-μm-co-laser-system)

 Written by [Convergent Dental](https://www.convergentdental.com/clinical-studies/author/convergent-dental) | Apr 2, 2020 6:45:16 PM

*Myron Nevins, Marc L Nevins, Stefano Parma-Benfenati, Marisa Roncati, Peter Schupbach, Chia-Yu Chen, Cosmin Sava, Catalin Sava, Mihaela Trifan, David M Kim*

[Click here](https://pubmed.ncbi.nlm.nih.gov/32032403/) for full study.

## ABSTRACT

This investigation was designed to evaluate the healing response of 9.3-μm CO2 laser-assisted periodontal therapy. Five patients presenting with moderate to severe periodontitis, with an initial pocket depth (PD) ≥ 5 mm and with teeth predetermined to be surgically extracted, were enrolled and consented to treatment with full-mouth CO2 laser-assisted therapy. The laser treatment was carried out in the Ultraguide Mode at a setting of 0.25-mm spot size, with an average power of 0.65 to 1.15 watts and 20% mist. The laser tip was passed from the gingival margin and down apically to the base of the pocket with a sweeping L motion. The teeth were intensely scaled with piezoultrasonic instrumentation afterwards. A second pass of the laser tip was performed for the study teeth. At 9 months, all patients were clinically reevaluated. For sites with an initial pocket depth of ≥ 7 mm, a mean PD reduction of 3.97 ± 1.36 mm and a mean clinical attachment level gain of 3.54 ± 1.54 mm were achieved, resulting in a mean PD of 3.91 ± 0.77 mm. En bloc biopsy samples of four teeth were obtained and analyzed; two demonstrated histologic evidence of new bone formation while the other two healed with a long junctional epithelium with minimal inflammatory infiltrate. Further long-term clinical studies are needed to investigate the treatment stability obtained with a 9.3-μm CO2 laser compared to conventional surgical therapy. Nevertheless, the encouraging clinical results indicated that adjunctive use of the 9.3-μm CO2 laser-assisted periodontal therapy can be beneficial for treatment of periodontally compromised patients.

[View full post](https://www.convergentdental.com/clinical-studies/clinical/human-clinical-and-histologic-evaluations-of-laser-assisted-periodontal-therapy-with-a-9-3-μm-co-laser-system)

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